Customized Biology Assay Solutions for Drug Discovery

Reliable and timely information about the biological activity of your compounds is critical for advancing drug discovery efforts. SCYNEXIS’ Discovery Biology Team develops and implements assays specifically to meet the needs of our partners, and can provide dedicated screening support for chemical discovery and lead optimization programs. High-throughput screening (HTS) platforms and automation enable the efficient evaluation of large numbers of samples. Our experience encompasses enzyme assays, cell-based assays, and bioassays utilizing model organisms such as the nematode C. elegans and the fruit fly Drosophila melanogaster, applied in therapeutic areas ranging from liver and metabolic function, oncology, and CNS disorders to infectious and parasitic diseases. Please contact us to discuss your customized solution needs.

Your Research Partner for Target Validation and Mechanism Elucidation

Our assay expertise can be coupled with biochemical, cellular, genetic, and pharmacological strategies to investigate the mechanism of action of your compounds and to validate novel drug targets, enabling new opportunities for your discovery programs. In addition, we can support your lead discovery efforts with in vitro assays for drug metabolism, drug transport, and counter-screens for unwanted mechanisms

Success with SCYNEXIS

SCYNEXIS Discovery Biology personnel have experience in the design of integrated, rational compound selection strategies spanning activities from in vitro screening to in vivo disease model testing. We have managed compound progression programs for partners from conceptualization through to successful preclinical candidate selection, working closely with chemistry colleagues to ensure timely delivery of results. Team members have diverse experience from pharmaceutical, biotechnology, and research institute settings, and are ready to apply the appropriate blend of expertise to meet your needs.