Innovative Drug Pipeline Solutions

Drug Outsourcing

MEDCHEM-FACTORY® High Throughput Purification & Analysis

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Core Capabilities

  • Purifies up to 2,500 samples per week
  • Delivers analogs in a variety of formats
  • Handles diverse structural properties
  • Real time analysis of progress and results through HEOS®
  • Rapid turnaround of samples

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MEDCHEM FACTORY Capabilties Sheet

Your Compounds, Faster and Better

Within the pharmaceutical industry, pure and well-characterized compounds are the prerequisite input for biological screening and lead optimization programs. SCYNEXIS has focused on efficiently delivering compounds of proven purity to our MEDCHEM-FACTORY® customers in a cost-effective manner. We have purified over 500,000 compounds to date.

Realization of our high-throughput purification and analysis system derives from the collaboration and integration of several expert groups: Medicinal Chemistry, Analytical Chemistry, Automation, and Information Technologies. This unique structure has created an enabling technology for discovery chemistry: the SCYNEXIS MEDCHEM-FACTORY® High-Throughput Synthesis, Purification and Characterization Platform.

Customer Focused

  • Ability to accept and/or deliver libraries in a variety of formats: plates, vials, etc.
  • Capability to purify compounds of diverse structural properties.
  • Demonstrate identity and quality using state-of-the-art analytical techniques: HPLC, Mass Spectrometry and High Throughput Flow NMR.
  • Focus on quality, recovery and speed.
  • Retrospective analysis and purification of corporate and third party collections.
  • Compound purity determined using various analytical tools coupled to LC: UV, MS, ELSD.

Data Reporting – HEOS®

  • Monitoring of the purification process and all analytical data by the customer.
  • Capability to utilize a variety of analytical techniques.
  • Fully flexible reporting formats.

Versatile Platform Capacity

  • Libraries: 10 to 100,000 member libraries.
  • Samples: 1 to 100’s of milligrams.
  • Capacity: Thousands of compounds purified per day.
  • QC: Each compound is analyzed for identity, purity and quantity.