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SCYNEXIS Receives Milestone Payment in Oncology Collaboration
with Merck & Co., Inc.

RESEARCH TRIANGLE PARK (October 27, 2009) - Drug discovery company SCYNEXIS, Inc. today announced that it has received a payment from Merck & Co., Inc. for achieving a preclinical milestone resulting from a collaboration to discover and develop novel oncology agents.

“We are pleased to celebrate success in reaching another milestone with our valued partner, Merck,” said Yves Ribeill, Ph.D., President and Chief Executive Officer of SCYNEXIS. “This milestone provides further validation of our long-term relationship with Merck in a number of therapeutic areas through discovery research and innovation.”

About SCYNEXIS
SCYNEXIS is a premier drug discovery and development company headquartered in Research Triangle Park, North Carolina. SCYNEXIS’ mission is to be the leader in delivering effective and innovative drug pipeline solutions to its pharmaceutical partners.

SCYNEXIS research teams integrate medicinal chemistry, advanced biological screening, computational chemistry, bioanalysis and analytical chemistry and use powerful, proprietary technologies such as the HEOS® Software Suite and MEDCHEMFACTORY® to advance molecules to candidate selection. SCYNEXIS development teams have been tailored to be especially effective in moving customer projects from the discovery phase to the clinic. SCYNEXIS process chemistry and bioanalytical departments operate under current GMP/GLP guidelines and have a strong track record of success. SCYNEXIS is registered with both the FDA and DEA. www.scynexis.com


Company Contact:

Terry Marquardt
SCYNEXIS, Inc.
terry.marquardt@scynexis.com
(919) 544-8600

Media Relations:
Rick Rountree
Rick Rountree Communications
rick@rickrountree.com

Sarah Cavanaugh
MacDougall Biomedical Communications
scavanaugh@macbiocom.com
(781) 235-3060