Posters and Presentations :: SCYNEXIS, Inc. (SCYX)

SCY-078 Demonstrates Significant Antifungal Activity in a Murine Model of Invasive Aspergillosis

SCY-078 Demonstrates Significant Antifungal Activity in a Murine Model of Invasive Aspergillosis

K. Borroto-Esoda, S. Barat, D. Angulo, C. Carruthers, K. Holden, P. Warn
IDWeek 2017
October 2017

Assessment of the <em>In Vitro</em> Antifungal Activity of SCY-078 Against a Collection of <em>C. parapsilosis</em> Clinical Isolates

Assessment of the In Vitro Antifungal Activity of SCY-078 Against a Collection of C. parapsilosis Clinical Isolates

S. Barat, D. Angulo, K. Borroto-Esoda, M. Ghannoum
IDWeek 2017
October 2017

SCY-078 Demonstrates Significant Tissue Penetration in Rats and Mice Following Oral or IV Administration

SCY-078 Demonstrates Significant Tissue Penetration in Rats and Mice Following Oral or IV Administration

S. Barat, K. Borroto-Esoda, D. Angulo, C. Carruthers
IDWeek 2017
October 2017

A Multicenter, Randomized, Evaluator Blinded, Active-Controlled Study to Evaluate the Safety and Efficacy of Oral SCY-078 vs. Oral Fluconazole in 96 Subjects with Moderate to Severe Vulvovaginal Candidiasis

A Multicenter, Randomized, Evaluator Blinded, Active-Controlled Study to Evaluate the Safety and Efficacy of Oral SCY-078 vs. Oral Fluconazole in 96 Subjects with Moderate to Severe Vulvovaginal Candidiasis

S. Helou, D. Angulo
IDSOG 2017
August 2017

The Effect of pH on the <em>In Vitro</em> Antifungal Activity of SCY-078

The Effect of pH on the In Vitro Antifungal Activity of SCY-078

E. Larkin, C. Hager, L. Long, N. Isham, S. Barat, K. Borroto-Esoda, S. Wring, D. Angulo, M. Ghannoum
IDSOG 2017
August 2017

Vaginal Concentrations of SCY-078, a Novel Glucan Synthase Inhibitor, Following Oral Administration in Mice

Vaginal Concentrations of SCY-078, a Novel Glucan Synthase Inhibitor, Following Oral Administration in Mice

S. Barat, K. Borroto-Esoda, S. Wring, D. Angulo
IDSOG 2017
August 2017

SCY-078, a Novel Intravenous and Oral Antifungal Agent, Demonstrates Extensive Tissue Distribution in Rats Following Single Intravenous Infusions and Oral Doses of [14C]SCY-078

SCY-078, a Novel Intravenous and Oral Antifungal Agent, Demonstrates Extensive Tissue Distribution in Rats Following Single Intravenous Infusions and Oral Doses of [14C]SCY-078

S. Wring, E. Solon, D, Watson, S. Barat, D. Angulo
ASM Microbe 2017
June 2017

Assessment of the <em>In Vitro</em> Antifungal Activity of SCY-078 Against a Panel of Susceptible and Resistant, Clinical <em>Candida</em> Isolates from Europe

Assessment of the In Vitro Antifungal Activity of SCY-078 Against a Panel of Susceptible and Resistant, Clinical Candida Isolates from Europe

K. Borroto-Esoda, S. Birchall, C. B. Moore, D. Angulo
ASM Microbe 2017
June 2017

Susceptibility Testing of SCY-078 Against <em>Candida</em> Isolates Obtained from a Clinical Study of Oral SCY-078 vs. Oral Fluconazole in Subjects with Moderate to Severe Vulvovaginal Candidiasis Demonstrates no Resistance Development

Susceptibility Testing of SCY-078 Against Candida Isolates Obtained from a Clinical Study of Oral SCY-078 vs. Oral Fluconazole in Subjects with Moderate to Severe Vulvovaginal Candidiasis Demonstrates no Resistance Development

K. Borroto-Esoda, D. Angulo, E. Larkin, I.Salem, L. Long, S. Helou, M. Ghannoum
ASM Microbe 2017
June 2017

Lack of an Effect of SCY-078, a Novel Antifungal Agent on QTc Interval in Healthy Subjects

Lack of an Effect of SCY-078, a Novel Antifungal Agent on QTc Interval in Healthy Subjects

G. Murphy, B. Darpo, T. Marbury, M. Hyman, D. Angulo
ASM Microbe 2017
June 2017