SCY-078 Demonstrates Significant Tissue Penetration in Rats and Mice Following Oral or IV Administration
S. Barat, K. Borroto-Esoda, D. Angulo, C. Carruthers
IDWeek 2017
October 2017
The Effect of pH on the In Vitro Antifungal Activity of SCY-078
E. Larkin, C. Hager, L. Long, N. Isham, S. Barat, K. Borroto-Esoda, S. Wring, D. Angulo, M. Ghannoum
IDSOG 2017
August 2017
Vaginal Concentrations of SCY-078, a Novel Glucan Synthase Inhibitor, Following Oral Administration in Mice
S. Barat, K. Borroto-Esoda, S. Wring, D. Angulo
IDSOG 2017
August 2017
Assessment of the In Vitro Antifungal Activity of SCY-078 Against a Panel of Susceptible and Resistant, Clinical Candida Isolates from Europe
K. Borroto-Esoda, S. Birchall, C. B. Moore, D. Angulo
ASM Microbe 2017
June 2017
Lack of an Effect of SCY-078, a Novel Antifungal Agent on QTc Interval in Healthy Subjects
G. Murphy, B. Darpo, T. Marbury, M. Hyman, D. Angulo
ASM Microbe 2017
June 2017
In vitro Interaction between SCY-078, Echinocandins and Azoles against Susceptible & Resistant Candida spp. Determined by the Checkerboard Method
K. Borroto-Esoda, B. Scorneaux, D. Angulo, S. Helou
ASM Microbe
June 2017
Evaluation of Antifungal Activity of SCY-078 in Combination with Other Antifungals Against Aspergillus Strains
L. Long, E. Larkin, K. Borroto-Esoda, S. Wring, D. Angulo, M. Ghannoum
27th European Congress of Clinical Microbiology and Infectious Diseases
April 2017
Effect of SCY-078 on the Pharmacokinetics of CYP2C8 substrate (Rosiglitazone) - Results from a Phase 1 Clinical Trial
D. Angulo, G. Atiee, C. Corr, M. Willett, G. Murphy, S. Wring
27th European Congress of Clinical Microbiology and Infectious Diseases
April 2017
Effect of SCY-078 on the Pharmacokinetics of Tacrolimus: Results from a Phase 1 Clinical Drug-Drug Interaction Trial
D. Angulo, G. Atiee, C. Corr, M. Willett, G. Murphy, S. Wring
27th European Congress of Clinical Microbiology and Infectious Diseases
April 2017
Activity of SCY-078 against Candida spp. obtained by EUCAST and CLSI procedures
L. Marcos-Zambrano, M. Gómez-Perosanz, P. Escribano, E. Bouza Santiago, J.Guinea
27th European Congress of Clinical Microbiology and Infectious Diseases
April 2017