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SCY-247
Ibrexafungerp
Life-threatening Infections
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SCY-247
Ibrexafungerp
Life-threatening Infections
Invasive Fungal Infections
Invasive Candidiasis
Invasive Aspergillosis
MARIO
Community Infections
Vulvovaginal Candidiasis
Recurrent VVC
Pipeline
Publications and Presentations
Our Science
Publications and Presentations
Date
Title
April 2025
Antifungal susceptibility testing of SCY-247 against contemporary clinical yeast isolates
ESCMID, April 2025
April 2025
SCY-247, a novel antifungal, demonstrates
in vitro
activity against genetically diverse
Candida auris
isolates, including
FKS1
mutants
ESCMID, April 2025
April 2025
The new triterpenoid antifungal SCY-247 retained activity against most echinocandin and fluconazole-resistant
Candida
spp isolates: reduced susceptibility against
C. glabrata
isolates showing substitutions at the first amino acid in hotspot 1
FKS2
gene
ESCMID, April 2025
April 2025
Assessment of
in vitro
activity of the new triterpenoid antifungal, SCY-247, against a collection of yeasts causing fungaemia in patients admitted to a tertiary hospital in Madrid from 2014 to 2024
ESCMID, April 2025
September 2024
SCY-247, A SECOND-GENERATION TRITERPENOID ANTIFUNGAL DEMONSTRATES BROAD TISSUE DISTRIBUTION AND EFFICACY IN MURINE FUNGAL INFECTION MODELS
MSGERC, September 2024
April 2024
The novel second-generation IV/oral triterpenoid SCY-247 is efficacious in an experimental murine model of invasive candidiasis caused by
Candida glabrata
ECCMID, April 2024
April 2024
SCY-247, a Novel Second-Generation IV/Oral Triterpenoid Antifungal, Demonstrates
In vitro
Activity Against Fungal Pathogens, Including Azole-Resistant Strains of Candida and
Aspergillus
ECCMID, April 2024
January 2024
SCY-247, a novel second-generation IV/oral triterpenoid antifungal, is efficacious in the neutropenic mouse model of pulmonary mucormycosis
AAAM, January 2024
October 2023
SCY-247, A SECOND-GENERATION IV/ORAL TRITERPENOID ANTIFUNGAL:
IN VITRO
ACTIVITY AGAINST A BROADSPECTRUM OF FUNGAL PATHOGENS, AND DOSE-DEPENDENT TISSUE DISTRIBUTION
IN VIVO
TIMM, October 2023
April 2023
Outcomes of Oral Ibrexafungerp in Subjects with Urinary Tract Infections from Two Phase 3 Open Label Studies: Difficult to Treat Invasive Fungal Infections (FURI) and Infections with
Candida auris
(CARES)
ECCMID, April 2023
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