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May 2026
Repeat Oral Dose SCY-247 Exceeds Exposures Associated with Efficacy in Murine Models of Invasive Candidiasis with Low Potential for Drug-Drug Interactions with Key CYP450s ICHS, May 2026
September 2025
SCY-247 demonstrates high in vitro activity against genetically diverse C. auris isolates, including FKS1 mutants TIMM, September 2025
September 2025
Three Months of SCY-247 EUCAST MIC Testing: Uniform Activity against Candida Species and no Cross-Resistance to Echinocandins TIMM, September 2025
September 2025
Efficacy of once or twice daily oral SCY-247, a second-generation triterpenoid antifungal, in a murine model of Candida auris infection TIMM, September 2025
September 2025
In vitro Efficacy of Second-Generation Triterpenoid Antifungal, SCY-247, against Multidrug- and Pandrug-resistant Candida auris TIMM, September 2025
September 2025
In vitro activity of SCY-247 and comparators against clinical isolates of Aspergillus spp. and Lomentospora prolificans TIMM, September 2025
September 2025
The Novel Second-Generation IV/Oral Triterpenoid SCY-247 Maintains In vitro and In vivo Activity against Resistant Candida glabrata TIMM, September 2025
April 2025
Antifungal susceptibility testing of SCY-247 against contemporary clinical yeast isolates ESCMID, April 2025
April 2025
SCY-247, a novel antifungal, demonstrates in vitro activity against genetically diverse Candida auris isolates, including FKS1 mutants ESCMID, April 2025
April 2025
The new triterpenoid antifungal SCY-247 retained activity against most echinocandin and fluconazole-resistant Candida spp isolates: reduced susceptibility against C. glabrata isolates showing substitutions at the first amino acid in hotspot 1 FKS2 gene ESCMID, April 2025
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