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SCY-247
Ibrexafungerp
Life-threatening Infections
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SCY-247
Ibrexafungerp
Life-threatening Infections
Invasive Fungal Infections
Invasive Candidiasis
Invasive Aspergillosis
MARIO
Community Infections
Vulvovaginal Candidiasis
Recurrent VVC
Pipeline
Publications and Presentations
Our Science
Publications and Presentations
Date
Title
September 2021
Outcomes of Candida Bone and Joint Infections in Eight Patients from a Phase 3 Open-label Study (FURI)
IDWeek
March 2021
A Second-Generation Fungerp Analog, SCY-247, Shows Potent In Vitro Activity against Candida auris and Other Clinically Relevant Fungal Isolates Antimicrobial Agents and Chemotherapy
Sherman Chu,
a,b
Lisa Long,
a,d
Rania Sherif,
a,d
Thomas S. McCormick,
a
Katyna Borroto-Esoda,
c
Stephen Barat,
c
Mahmoud A. Ghannouma,
d
March 2021
A Second-Generation Fungerp Analog, SCY-247, Shows Potent In Vivo Activity in a Murine Model of Hematogenously Disseminated Candida albicans Antimicrobial Agents and Chemotherapy
Sherman Chu,
a,b
Lisa Long,
a,d
Thomas S. McCormick,
a
Katyna Borroto-Esoda,
c
Stephen Barat
c
Mahmoud A. Ghannouma,d
October 2020
Efficacy and Safety of Oral Ibrexafungerp in 41 Patients with Refractory Fungal Diseases, Interim Analysis of a Phase 3 Open-label Study (FURI)
BD Alexander, OA Cornely, PG Pappas, R Miller, M Johnson, J Vazquez, L Ostrosky-Zeichner, A Spec, R Rautemaa-Richardson, R Krause, GR Thompson, TJ Walsh, CG Morse, JW Sanders, D Andes, GM Lyon, FM Marty, MH Miceli, TF Patterson, M Hoenigl, N Azie, DA Angulo
ID Week
October 2020
Ibrexafungerp Demonstrates Potent and Consistent
In Vitro
Activity Against >400 Global
Candida auris
Isolates, Including Isolates with Elevated MIC’s to Echinocandins
N. Azie, K. Borroto-Esoda, D. Angulo
ID Week
June 2020
Determination of Antifungal Activity of SCY-078, a Novel Glucan Synthase Inhibitor, Against a broad panel of Rare Pathogenic Fungi
M. Ghannoum, L. Long, R. Sherif, F. Z. Abidi, K. Borroto-Esoda, S. Barat, D. Angulo, N. Wiederhold
ASM Microbe Online
June 2020
Delayed Initiation of the Novel Oral Glucan Synthase Inhibitor, Ibrexafungerp, is Effective in a Murine Model of Invasive Candidiasis caused by
Candida auris
N.P. Wiederhold, L.K. Najvar, R. Jaramillo, M. Olivo, H. Patterson, S. Barat, K. Borroto-Esoda, G. Catano, T.F. Patterson
UT Health San Antonio, South Texas Veterans Health Care System, SCYNEXIS, Inc.
ASM Microbe Online
April 2020
Prevention of
Pneumocystis
Pneumonia by Ibrexafungerp in a Murine Prophylaxis Model
Stephen Barat, Katyna Borroto-Esoda, Alan Ashbaugh, Melanie Cushion
ECCMID 2020
April 2020
CANDIMAD study: a prospective multi-centre laboratory based survey of antifungal resistance in
Candida
spp. causing invasive candidiasis in Madrid
Judith Diaz-Garcia, Aina Mesquida, María Ángeles Meléndez Carmona, Fernando González-Romo, Cuetara Maria Soledad, Nelly Daniela Zurita Cruz, Maria Muñoz Algarra, Maria Del Coral Garcia, Aída Sánchez, Inmaculada Quiles, Maria Teresa Duran-Valle, Carlos Sanchez-Carrillo, Patricia Muñoz, Pilar Escribano, Jesus Guinea Ortega
February 2020
In vitro
Evaluation of Combination of Ibrexafungerp and Azoles against
Aspergillus
spp. Isolated from Lung Transplant Recipients
Vidya Jagadeesan, Eileen Driscoll, Binghua Hao, Stephen Barat, Katyna Borroto-Esoda, Tom Chen, David Angulo, Cornelius J Clancy, M. Hong Nguyen
AAAM 2020
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